Endocrine Abstracts

Background: The goals of acromegaly treatment are to achieve long-term biochemical control, control tumor size and decrease the risk of developing systemic comorbidities. Moreover, from the patient’s perspective, symptoms and QoL are critical parameters of disease control and should be assessed routinely. To aid in the global clinical management of acromegaly, a holistic clinical decision support tool, the Acromegaly Disease Activity Tool (ACRODAT®) was developed.</p...

Introduction: Ectopic Cushing Syndrome (ECS) is a rare disease associated with significant comorbidity. Among the causes of Cushing’s syndrome (CS), ACTH-producing extrahypophyseal tumours are rarely reported. The aim of our study is to describe the clinical, diagnostic and therapeutic characteristics of patients with ECS treated in our Endocrinology department over a 15-year period.Methods: A cross-sectional unicentric retrospective study was desi...

Background: Inferior petrosal sinus sampling (IPSS) is indicated in the diagnosis of adrenocor-ticotropic hormone (ACTH)-dependent Cushing’s syndrome (CS), especially when the results of the initial diagnostic tests are discordant.Objective: To describe the patients who underwent this invasive functional test in a tertiary hospital.Methods: This was an observational study of a retrospective cohort of patients with ACTH- depend...

Introduction: Lutetium-177-DOTATATE (Lu177) is approved in patients with well-differentiated (G1 and G2) neuroendocrine tumors (NETs) positive to somatostatin receptors, progressive and unresectable or metastatic. Lu177 has been shown to increase progression-free survival and the quality of life of these patients.Material and Methods: Retrospective descriptive study of a series of 15 cases with NETs treated with Lu177. Demographic data, tumor characteris...